BCR Meaning and
Definition
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BCR is an acronym that stands for "B-cell receptor." It refers to a crucial component of B-cells, which are a type of white blood cell involved in the immune response of the body. The B-cell receptor is a membrane-bound protein complex found on the surface of B-cells, playing a central role in recognizing and binding to specific antigens.
The BCR consists of two main components: the antigen-binding complex and the signaling complex. The antigen-binding complex is responsible for the recognition and binding of foreign substances, known as antigens, such as pathogens or toxins. This complex is composed of two identical heavy chains and two identical light chains, which combine to form antigen-binding sites.
When the BCR binds to an antigen, it triggers a series of signaling events through the signaling complex, leading to B-cell activation and subsequent immune responses. This activation leads to the production of antibodies that are specific to the antigen, helping to neutralize or eliminate the foreign invader.
BCR plays a critical role in the adaptive immune system, as it allows B-cells to recognize and initiate an immune response against a wide range of antigens. Dysfunction or abnormalities in the BCR can lead to various immune-related disorders, including autoimmune diseases and immunodeficiencies. Understanding the structure and function of BCR is therefore vital for advancing research and developing therapies related to immune system disorders.
Common Misspellings for BCR
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