TCR ALPHA BETA Meaning and
Definition
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T-cell receptor alpha beta (TcR αβ) is a type of heterodimeric receptor found on the surface of T-cells, a type of white blood cell, which plays a crucial role in the immune system. The TcR αβ consists of two protein chains, namely the alpha chain (TcRα) and the beta chain (TcRβ), that are involved in recognizing and binding to specific antigens.
The TcR αβ is responsible for recognizing antigens presented by antigen-presenting cells (APCs) through the major histocompatibility complex (MHC) molecules. It allows the T-cell to differentiate between self and non-self cells by interacting with antigen-derived peptides displayed on the surface of the infected or abnormal cells. This recognition initiates a cascade of immune responses, including the activation and proliferation of T-cells to eradicate the foreign pathogen or abnormal cells.
The TcR αβ possesses highly diverse and specific binding capabilities, enabling it to recognize a vast array of antigens. This diversity is achieved through genetic recombination during T-cell development, resulting in a wide range of TcR αβ molecules with distinct antigen-binding specificities.
The TcR αβ is crucial for adaptive immune responses, facilitating the recognition, and elimination of intracellular pathogens, such as viruses and bacteria, as well as cancerous cells. It plays a vital role in orchestrating immune defenses and inflammation, thereby maintaining immune homeostasis and protecting the body against harmful invaders.
Common Misspellings for TCR ALPHA BETA
- rcr alpha beta
- fcr alpha beta
- gcr alpha beta
- ycr alpha beta
- 6cr alpha beta
- 5cr alpha beta
- txr alpha beta
- tvr alpha beta
- tfr alpha beta
- tdr alpha beta
- tce alpha beta
- tcd alpha beta
- tcf alpha beta
- tct alpha beta
- tc5 alpha beta
- tc4 alpha beta
- tcr zlpha beta
- tcr slpha beta
- tcr wlpha beta
- tcr qlpha beta
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