SECRETORY IMMUNOGLOBULIN A Meaning and
Definition
-
Secretory immunoglobulin A (SIgA) is a type of antibody that plays a crucial role in the immune system's defense against pathogens and foreign substances. It is primarily found in the mucosal secretions of various mucous membranes, including those lining the respiratory, gastrointestinal, and genitourinary tracts.
SIgA is a complex molecule composed of two main components: a secretory component and two immunoglobulin A (IgA) molecules. The secretory component facilitates the transport of SIgA across epithelial cells, allowing it to be present in various bodily fluids such as saliva, tears, breast milk, and mucus.
The main function of SIgA is to provide localized immunity in mucosal areas, acting as the first line of defense against pathogens that attempt to invade these surfaces. It achieves this by neutralizing or inhibiting the attachment of these pathogens to host cells, thereby preventing their entry and subsequent infection. Additionally, SIgA can enhance the removal of pathogens by promoting their clearance through mucus and allowing for their elimination through bodily secretions.
SIgA also assists in maintaining the balance of the gut microbiota and preventing immune responses to harmless antigens in the gut, creating tolerance to dietary antigens and commensal bacteria.
Overall, secretory immunoglobulin A is a critical component of the immune system that provides localized protection against pathogens and aids in maintaining a healthy mucosal environment.
Common Misspellings for SECRETORY IMMUNOGLOBULIN A
- aecretory immunoglobulin a
- zecretory immunoglobulin a
- xecretory immunoglobulin a
- decretory immunoglobulin a
- eecretory immunoglobulin a
- wecretory immunoglobulin a
- swcretory immunoglobulin a
- sscretory immunoglobulin a
- sdcretory immunoglobulin a
- srcretory immunoglobulin a
- s4cretory immunoglobulin a
- s3cretory immunoglobulin a
- sexretory immunoglobulin a
- sevretory immunoglobulin a
- sefretory immunoglobulin a
- sedretory immunoglobulin a
- seceetory immunoglobulin a
- secdetory immunoglobulin a
- secfetory immunoglobulin a
- sectetory immunoglobulin a
Infographic
Add the infographic to your website:
