JURKAT CELLS Meaning and
Definition
-
Jurkat cells are a line of immortalized human T lymphocyte cells widely used in scientific research and laboratory investigations. These cells are derived from a patient suffering from acute T-cell leukemia, making them a valuable tool for studying various aspects of T-cell biology, immunology, and the role of proteins in signaling pathways.
Jurkat cells are characterized by their monoclonal origin, meaning they are derived from a single cell and possess identical genetic features. They are widely used as a model system to understand T-cell activation, proliferation, gene expression, and apoptosis. This well-established cell line is often employed in experiments related to cancer research, drug development, and immune system function.
These cells exhibit a variety of properties commonly seen in normal T lymphocytes, such as surface expression of various markers like CD3, CD4, and CD8. However, they lack some functional features normally observed in primary T-cells, such as antigen-specific responses. Nevertheless, they serve as a valuable research tool due to their advantages, including ease of cultivation, rapid growth rate, and high transfection efficiency.
Overall, Jurkat cells are a widely recognized and utilized research tool that allows scientists to investigate important aspects of T-cell biology and immune function. Their contribution to advancing our understanding of cellular processes and disease mechanisms cannot be overstated.
Common Misspellings for JURKAT CELLS
- hurkat cells
- nurkat cells
- murkat cells
- kurkat cells
- iurkat cells
- uurkat cells
- jyrkat cells
- jhrkat cells
- jjrkat cells
- jirkat cells
- j8rkat cells
- j7rkat cells
- juekat cells
- judkat cells
- jufkat cells
- jutkat cells
- ju5kat cells
- ju4kat cells
- jurjat cells
- jurmat cells
Etymology of JURKAT CELLS
The word "Jurkat cells" is derived from the name of a patient, Georg Julius Jurkat, who suffered from a type of cancer called acute T-cell leukemia. In the early 1970s, scientists obtained a cell line from Jurkat's blood that carried the cancerous T-cells. These cells were subsequently named after the patient as "Jurkat cells" in his honor. Today, Jurkat cells are widely used in biomedical research, particularly in the studies of immunology, cancer, and virology.
Infographic
Add the infographic to your website:
