CREATINE PHOSPHOKINASE Meaning and
Definition
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Creatine phosphokinase, commonly known as CK or CPK, is an enzyme found in various tissues of the human body, particularly in the heart, brain, and skeletal muscles. It plays a crucial role in energy metabolism by facilitating the conversion of creatine phosphate to creatine and adenosine triphosphate (ATP). ATP serves as the primary energy source for cellular activities.
Creatine phosphokinase exists in three isoforms - CK-MM, CK-MB, and CK-BB - each found in different tissues. CK-MM is present predominantly in skeletal muscles, CK-MB is mainly found in cardiac muscle, while CK-BB is primarily located in the brain and smooth muscles. These isoforms provide clinicians with valuable information in diagnosing different conditions.
Elevated levels of creatine phosphokinase in the blood are indicative of muscle damage or injury, as this enzyme is released into the bloodstream when there is muscle breakdown. Therefore, the measurement of CK levels can be used to diagnose various muscle-related conditions, such as muscular dystrophy, myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), and other forms of muscle injury.
Creatine phosphokinase is commonly measured through a blood test. The results are reported as the total CK level or as specific isoforms, depending on the suspected condition. Interpretation of CK levels should always take into account the individual's clinical symptoms and medical history, as well as other diagnostic tests.
In summary, creatine phosphokinase is an enzyme that plays a crucial role in energy metabolism, specifically in the conversion of creatine phosphate to ATP. It is used as a diagnostic marker for various muscle-related conditions and is commonly measured through a blood test.
Common Misspellings for CREATINE PHOSPHOKINASE
- xreatine phosphokinase
- vreatine phosphokinase
- freatine phosphokinase
- dreatine phosphokinase
- ceeatine phosphokinase
- cdeatine phosphokinase
- cfeatine phosphokinase
- cteatine phosphokinase
- c5eatine phosphokinase
- c4eatine phosphokinase
- crwatine phosphokinase
- crsatine phosphokinase
- crdatine phosphokinase
- crratine phosphokinase
- cr4atine phosphokinase
- cr3atine phosphokinase
- creztine phosphokinase
- crestine phosphokinase
- crewtine phosphokinase
- creqtine phosphokinase
Etymology of CREATINE PHOSPHOKINASE
The word "creatine" in "Creatine Phosphokinase" comes from the Greek word "kreas", meaning flesh. "Creatine" refers to a compound found in muscle tissue.
The term "phospho-" indicates the presence of a phosphate group, derived from the Greek word "phosphoros" meaning "light-producing" or "light-bringer".
"Kinase" is derived from the Greek word "kinēsis", meaning motion. In biochemistry, "kinase" refers to an enzyme that catalyzes the transfer of a phosphate group from adenosine triphosphate (ATP) to a specific molecule.
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