COIII GENE PRODUCT Meaning and
Definition
-
The COIII gene product, also known as the cytochrome c oxidase subunit III, is a protein encoded by the COIII gene. It is a key component of the mitochondrial electron transport chain complex IV, which is responsible for the final step in the aerobic respiration process, involving the transfer of electrons to oxygen, ultimately forming water. This protein plays a critical role in the catalytic activity of complex IV, aiding in the transmembrane transfer of electrons.
The COIII gene product is responsible for facilitating the assembly and stabilization of the mitochondrial cytochrome c oxidase complex. It is primarily localized in the inner mitochondrial membrane, where it binds to other subunits to form the functional complex. This protein contains conserved domains that are crucial for its enzymatic function, including the heme binding sites necessary for the binding and transfer of electrons.
Mutations or defects in the COIII gene product can lead to mitochondrial dysfunctions and disruptions in oxidative phosphorylation. These alterations can result in various mitochondrial diseases and disorders, such as Leigh syndrome, cytochrome c oxidase deficiency, or other rare respiratory chain disorders. Consequently, studying the COIII gene product and its associated mutations can provide valuable insights into mitochondrial biology and the pathogenesis of related disorders.
In summary, the COIII gene product is a protein involved in the assembly and function of the mitochondrial cytochrome c oxidase complex, playing a crucial role in the mitochondrial electron transport chain and aerobic respiration.
Common Misspellings for COIII GENE PRODUCT
- xoiii gene product
- voiii gene product
- foiii gene product
- doiii gene product
- ciiii gene product
- ckiii gene product
- cliii gene product
- cpiii gene product
- c0iii gene product
- c9iii gene product
- couii gene product
- cojii gene product
- cokii gene product
- cooii gene product
- co9ii gene product
- co8ii gene product
- coiui gene product
- coiji gene product
- coiki gene product
- coioi gene product
Infographic
Add the infographic to your website:
