How Do You Spell CMP SIALIC ACID SYNTHETASE?

1. CMP Sialic Acid Synthetase is an enzyme that plays a crucial role in the biosynthesis of sialic acid, also known as N-acetylneuraminic acid (Neu5Ac) in living organisms.

   Sialic acids are a family of nine-carbon alpha-keto acids with a uniquely structured nine-carbon backbone, which are widely distributed throughout various tissues and fluids in the body. These important monosaccharides are primarily found on the outer surfaces of cell membranes and play essential roles in many biological processes, including cellular recognition, immune response modulation, and host-pathogen interactions.

   CMP Sialic Acid Synthetase is responsible for catalyzing the final step of the sialic acid biosynthesis pathway. Specifically, it uses cytidine 5'-monophosphate (CMP) and N-acetylmannosamine (ManNAc) as substrates to generate CMP-sialic acid. This reaction involves the transfer of the acetyl group from N-acetylmannosamine to cytidine monophosphate, resulting in the production of CMP-sialic acid as the final product.

   The activity of CMP Sialic Acid Synthetase is crucial for the regulation of sialic acid levels in cells and tissues. Dysregulation or deficient activity of this enzyme can lead to various metabolic disorders and diseases, including cancer, immunological disorders, and neurological disorders. Furthermore, CMP Sialic Acid Synthetase is an attractive target for drug development and therapeutic interventions aimed at modulating sialic acid levels and function in pathological conditions.

Common Misspellings for CMP SIALIC ACID SYNTHETASE