CLEAR CELL SARCOMAS Meaning and
Definition
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Clear cell sarcomas, also known as melanoma of soft parts, is a rare and aggressive form of soft tissue cancer that primarily affects young adults and adolescents. It is called clear cell sarcoma due to the presence of clear, transparent cells in the tumor, which can be seen under a microscope. These tumors commonly arise in the tendons or aponeuroses, which are the fibrous tissues that connect muscles to bone or provide attachments for muscle expansion.
Clear cell sarcomas often exhibit specific genetic abnormalities, particularly a fusion between the EWSR1 gene and the ATF1 gene. This fusion results in the formation of a chimeric protein that may contribute to the development and progression of the tumor. However, the exact cause of clear cell sarcomas is still not fully understood.
Symptoms of clear cell sarcomas may include a painless mass or lump in the affected area, limited joint motion, or numbness in the surrounding nerves. Diagnosis of this condition involves a thorough clinical examination, imaging tests such as X-rays or MRI scans, and a biopsy to confirm the presence of clear cell sarcoma cells.
Treatment for clear cell sarcomas typically involves a combination of surgery, radiation therapy, and chemotherapy. Due to the rarity and aggressiveness of this cancer, it often requires a multidisciplinary approach involving various specialists to optimize treatment outcomes. Regular follow-ups and monitoring are crucial, as clear cell sarcomas are prone to metastasize to distant sites such as the lungs or lymph nodes.
Common Misspellings for CLEAR CELL SARCOMAS
- xlear cell sarcomas
- vlear cell sarcomas
- flear cell sarcomas
- dlear cell sarcomas
- ckear cell sarcomas
- cpear cell sarcomas
- coear cell sarcomas
- clwar cell sarcomas
- clsar cell sarcomas
- cldar cell sarcomas
- clrar cell sarcomas
- cl4ar cell sarcomas
- cl3ar cell sarcomas
- clezr cell sarcomas
- clesr cell sarcomas
- clewr cell sarcomas
- cleqr cell sarcomas
- cleae cell sarcomas
- clead cell sarcomas
- cleaf cell sarcomas
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