CETP Meaning and
Definition
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CETP, or Cholesteryl Ester Transfer Protein, is an enzyme that plays a vital role in the metabolism of lipids, particularly in the process of cholesterol transport within the body. It is responsible for facilitating the transfer of cholesteryl esters (a compound derived from cholesterol) and triglycerides between different lipoprotein particles, which are specialized proteins that transport lipids in the bloodstream.
The CETP enzyme functions primarily in the exchange of cholesteryl esters from high-density lipoproteins (HDL), commonly known as "good cholesterol," with triglycerides from very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL), often referred to as "bad cholesterol." By mediating this lipid transfer, CETP assists in the redistribution of cholesterol within lipoproteins, regulating their composition and aiding in the transport of cholesterol from peripheral tissues back to the liver for excretion.
The activity of CETP is crucial in maintaining a healthy lipid profile and preventing the accumulation of cholesterol in arterial walls, which can potentially lead to atherosclerosis and cardiovascular diseases. Genetic mutations affecting CETP have been associated with abnormalities in cholesterol metabolism and an increased risk of coronary artery disease.
Pharmaceutical research has explored CETP inhibitors as potential therapeutic agents for managing dyslipidemia and preventing cardiovascular events. These inhibitors function by blocking CETP activity and thereby increasing HDL cholesterol levels while reducing LDL cholesterol levels. However, their clinical efficacy and long-term effects are still a subject of ongoing research and debate.
Common Misspellings for CETP
- xcetp
- cxetp
- vcetp
- cvetp
- fcetp
- cfetp
- cewtp
- c4etp
- ce4tp
- c3etp
- ce3tp
- cetgp
- ce6tp
- cet6p
- ce5tp
- cet5p
- cet0p
- cetp0
- cetpp
- c etp
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