CALCIOL Meaning and
Definition
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Calciol is a term commonly used in the field of biochemistry and physiology to refer to a chemical compound known as 25-hydroxycholecalciferol. Also referred to as calcidiol, it is a metabolite of cholecalciferol, which is a form of Vitamin D synthesized in the skin upon exposure to sunlight. Calciol is also obtained through dietary intake of animal sources, such as fish, eggs, and dairy products.
As a prohormone, calciol acts as the precursor to the biologically active form of Vitamin D, known as calcitriol. In the liver, cholecalciferol is converted to calcidiol by the enzyme 25-hydroxylase, a process that occurs during the first step of Vitamin D metabolism. Calcidiol then undergoes further conversion in the kidneys through the action of the enzyme 1α-hydroxylase, resulting in the production of calcitriol.
Calciol plays a crucial role in maintaining calcium and phosphate homeostasis and promoting bone mineralization. It aids in the absorption of calcium and phosphate from the intestine and helps regulate their levels in the bloodstream. Calciol is also involved in various physiological processes, including the regulation of immune function, cell growth, and modulation of gene expression.
Measurement of the level of calciol in blood can be used as an indicator of an individual's Vitamin D status, with lower levels indicating deficiency. Supplementation with cholecalciferol is commonly recommended to address Vitamin D deficiency and ensure adequate amounts of calciol for optimal health.
Common Misspellings for CALCIOL
- xalciol
- valciol
- falciol
- dalciol
- czlciol
- cslciol
- cwlciol
- cqlciol
- cakciol
- capciol
- caociol
- calxiol
- calviol
- calfiol
- caldiol
- calcuol
- calcjol
- calckol
- calcool
- calc9ol
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