BETA HYDROXYACYL DEHYDROGENASES Meaning and
Definition
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Beta hydroxyacyl dehydrogenases, also known as BHDH, are a group of enzymes that play a crucial role in lipid metabolism. These enzymes are primarily involved in the oxidation of hydroxyacyl-CoA compounds, which are intermediates formed during the breakdown of fatty acids in cells.
The term "beta" in beta hydroxyacyl dehydrogenases refers to the position of the hydroxyl group (-OH) on the fatty acid chain. This enzymatic group catalyzes the transfer of hydrogen atoms from the beta carbon, adjacent to the hydroxyl group, to the corresponding NAD+ or NADP+ coenzyme. This reaction results in the reduction of the coenzyme and the subsequent generation of NADH or NADPH, respectively.
The beta hydroxyacyl dehydrogenases are essential in the metabolism of fatty acids, as they are responsible for the conversion of beta hydroxyacyl-CoA derivatives to ketoacyl-CoA compounds. This conversion enables the release of energy through the process of beta-oxidation, which occurs in the mitochondria of cells. Additionally, beta hydroxyacyl dehydrogenases also participate in the biosynthesis of fatty acids, contributing to the production of various lipids required for cellular processes.
Due to their critical role in lipid metabolism, alterations or deficiencies in beta hydroxyacyl dehydrogenases have been associated with various metabolic disorders, including defects in the beta-oxidation of fatty acids. Understanding the function and mechanisms of these enzymes is essential for elucidating the biological processes underlying lipid metabolism and for developing potential therapeutic interventions for related disorders.
Common Misspellings for BETA HYDROXYACYL DEHYDROGENASES
- veta hydroxyacyl dehydrogenases
- neta hydroxyacyl dehydrogenases
- heta hydroxyacyl dehydrogenases
- geta hydroxyacyl dehydrogenases
- bwta hydroxyacyl dehydrogenases
- bsta hydroxyacyl dehydrogenases
- bdta hydroxyacyl dehydrogenases
- brta hydroxyacyl dehydrogenases
- b4ta hydroxyacyl dehydrogenases
- b3ta hydroxyacyl dehydrogenases
- bera hydroxyacyl dehydrogenases
- befa hydroxyacyl dehydrogenases
- bega hydroxyacyl dehydrogenases
- beya hydroxyacyl dehydrogenases
- be6a hydroxyacyl dehydrogenases
- be5a hydroxyacyl dehydrogenases
- betz hydroxyacyl dehydrogenases
- bets hydroxyacyl dehydrogenases
- betw hydroxyacyl dehydrogenases
- betq hydroxyacyl dehydrogenases
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