ALPHA LYMPHOTOXIN Meaning and
Definition
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Alpha Lymphotoxin, also known as Lymphotoxin-alpha (LT-α) or Tumor Necrosis Factor-beta (TNF-β), is a protein molecule that belongs to the tumor necrosis factor (TNF) superfamily. It is primarily produced by activated T cells and plays a critical role in immune responses and inflammation regulation.
Alpha Lymphotoxin is involved in various physiological processes, primarily including the development and organization of lymphoid tissues, such as lymph nodes and Peyer's patches. It functions through interactions with its receptors, LT-β receptor (LTβR) and TNF receptor type 1 (TNFR1).
The protein serves as a potent pro-inflammatory cytokine, stimulating the production of other inflammatory molecules and promoting the migration of immune cells to sites of infection or injury. It enhances the expression of adhesion molecules on endothelial cells, facilitating leukocyte recruitment to inflamed tissues.
Furthermore, Alpha Lymphotoxin is essential for the formation of lymphoid follicles and the differentiation of lymphocytes within these structures. It promotes the interactions between lymphocytes and stromal cells, which are crucial for proper functioning of the immune system.
Although considered a crucial mediator of immune responses, excessive production of Alpha Lymphotoxin has been implicated in the pathogenesis of various inflammatory diseases, including rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis. Additionally, dysregulation of this protein has been associated with certain types of cancers and autoimmune disorders.
In summary, Alpha Lymphotoxin is a protein molecule that is essential for immune responses and lymphoid tissue development. However, its dysregulation can contribute to the pathogenesis of several diseases.
Common Misspellings for ALPHA LYMPHOTOXIN
- zlpha lymphotoxin
- slpha lymphotoxin
- wlpha lymphotoxin
- qlpha lymphotoxin
- akpha lymphotoxin
- appha lymphotoxin
- aopha lymphotoxin
- aloha lymphotoxin
- allha lymphotoxin
- al-ha lymphotoxin
- al0ha lymphotoxin
- alpga lymphotoxin
- alpba lymphotoxin
- alpna lymphotoxin
- alpja lymphotoxin
- alpua lymphotoxin
- alpya lymphotoxin
- alphz lymphotoxin
- alphs lymphotoxin
- alphw lymphotoxin
Etymology of ALPHA LYMPHOTOXIN
The word "alpha Lymphotoxin" is a compound term formed by combining "alpha" and "Lymphotoxin".
- "Alpha" is derived from the Greek letter "alpha" (Α, α), which is the first letter of the Greek alphabet. It is commonly used to denote the first or initial element of a series. In the context of scientific terminology, "alpha" often refers to the primary or most important form of a particular substance or entity.
- "Lymphotoxin" is a compound word combining "lympho-" and "-toxin". "Lympho-" is derived from the term "lymph", referring to a fluid found in the lymphatic system, which plays a vital role in immune responses. "-Toxin" is a suffix indicating a poisonous or harmful substance.
Similar spelling word for ALPHA LYMPHOTOXIN
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