ALPHA HELIX Meaning and
Definition
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The alpha helix is a structural motif commonly found in proteins, often associated with their secondary structure. It is characterized by a right-handed coiled structural arrangement of the polypeptide chain, resembling a spiral staircase. The alpha helix forms through hydrogen bonding between the oxygen atom of the carboxyl group and the hydrogen atom of the amine group, which are four amino acids apart in the amino acid sequence.
In an alpha helix, each amino acid residue has a defined and specific position, and they are tightly packed together. The backbone of the alpha helix is tightly coiled, while the amino acid side chains project outward. This structural conformation imparts stability and rigidity to the protein molecule.
The alpha helix is an essential structural element that contributes to the folding and overall stability of proteins. It plays a crucial role in protein-protein interactions and the formation of protein domains. Moreover, it allows for an efficient packaging of the protein chain within a compact three-dimensional structure.
The alpha helix is often observed in regions of proteins that span cell membranes or those involved in protein-ligand interactions. It is also commonly found in fibrous proteins like keratin and in certain enzymes and regulatory molecules. Understanding the presence and behavior of the alpha helix is crucial for predicting the protein's functionality, folding, and intermolecular interactions.
Common Misspellings for ALPHA HELIX
- zlpha helix
- slpha helix
- wlpha helix
- qlpha helix
- akpha helix
- appha helix
- aopha helix
- aloha helix
- allha helix
- al0ha helix
- alpga helix
- alpba helix
- alpna helix
- alpja helix
- alpua helix
- alpya helix
- alphz helix
- alphs helix
- alphw helix
- alphq helix
Etymology of ALPHA HELIX
The word "alpha helix" is derived from two different origins.
First, "alpha" comes from the Greek alphabet, where it is the first letter. In the context of the alpha helix, "alpha" refers to the fact that this particular type of helix is the most common and refers to its structural properties.
Second, "helix" comes from the Greek word "helix" (ἕλιξ), which means spiral or twisted. The term "helix" was first used in mathematics to describe a three-dimensional curve that forms a spiral shape. It was later adapted in biology to describe this specific structure.
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